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Cord Blood Stem Cells Treatment


CORD BLOOD IS CURRENTLY UTILIZED IN THE TREATMENT OF AROUND 80 DISEASES*
Including different types of lymphoma and anaemia. By saving the cord blood of your baby, you are therefore getting a potentially lifesaving option available for your child, and your family.


TIME TO SHARE THE LOVE AND GUIDANCE
Your child is able to use his stem cells when the need arises, this is known as Autologous Transplant. However, it can also be shared by the siblings in the family after suitable matching; such cases are known as Allogeneic Transplant.
Hematopoietic cell transplantation (HCT) of umbilical cord origin can benefit for malignant and nonmalignant diseases like Fanconi’s anemia, aplastic anemia, leukemias, bone marrow failure syndromes, inborn error of metabolism, congenital disorders and hemoglobinopathies

Note: The Sources of disease information are publications in the medical literature that were found by keyword searches of PubMed and Google Scholar. All these are cited in our “Literature & References” page.


DISEASES TREATABLE WITH CORD BLOOD BANKING
Diseases that may be treated with cord blood transplant as standard treatment include:

Diseases Cord Blood Transplant “Standard Treatment”
Blood Disorders Leukemia is a cancer of the immune system, where the cells are called leukocytes or white cells Acute Lymphoblastic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Biphenotypic Leukemia
Acute Undifferentiated Leukemia
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)
Myelodysplastic Syndromes are also called pre-leukemia
Myelodysplastic Syndromes are also called pre-leukemia Refractory Anemia
Refractory Anemia with Ringed Sideroblasts (Sideroblastic anemia)
Refractory Anemia with Excess Blasts
Refractory Anemia with Excess Blasts in Transformation
Chronic Myelomonocytic Leukemia (CMML)
Lymphomas is a solid tumors of   leukocytes that circulate in the blood and lymph vessels Hodgkin’s Lymphoma                     

 

Non-Hodgkin’s Lymphoma including Burkitt’s Lymphoma
Blood cell proliferation disorders Anemias are deficiencies or malformations of red cells Fanconi Anemia

(The first cord blood transplant in 1988 was for FA, an inherited disorder

Congenital Dyserythropoietic Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Inherited Red Cell Abnormalities
Sickle Cell Disease
Beta Thalassemia Major (aka Cooley’s Anemia)
Diamond-Blackfan Anemia
Pure Red Cell Aplasia
Inherited Platelet Abnormalities
Amegakaryocytosis / Congenital Thrombocytopenia
Glanzmann Thrombasthenia
Inherited Immune System Disorders Severe Combined Immunodeficiency SCID with Adenosine Deaminase Deficiency (ADA-SCID)

 

SCID which is X-linked
SCID with absence of T & B Cells
SCID with absence of T Cells, Normal B Cells
Omenn Syndrome
Neutropenias

 

Infantile Genetic Agranulocytosis (Kostmann Syndrome)
Myelokathexis
Others Ataxia-Telangiectasia
Bare Lymphocyte Syndrome
DiGeorge Syndrome
Hemophagocytic Lymphohistiocytosis
Leukocyte Adhesion Deficiency
Leukocyte Adhesion Deficiency
Lymphoproliferative Disorder, X-linked (Susceptibility to Epstein-Barr virus)
Wiskott-Aldrich Syndrome
Myeloproliferative Disorders
Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Polycythemia Vera
Essential Thrombocythemia
Phagocyte Disorders

 

These are immune system cells that engulf and kill foreign organisms Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis
Bone Marrow Cancers Multiple Myeloma
Plasma Cell Leukemia
Waldenstrom’s Macroglobulinemi
Inherited Disorders of the Immune System & Other Organs Cartilage-Hair Hypoplasia

 

Erythropoietic Porphyria
Hermansky-Pudlak Syndrome
Pearson’s Syndrome
Shwachman-Diamond Syndrome
Systemic Mastocytosis
Inherited Metabolic Disorders Mucopolysaccharidosis (MPS) Storage Diseases Hurler Syndrome (MPS-IH)
 

.

Scheie Syndrome (MPS-IS)
Hunter Syndrome (MPS-II)
Sanfilippo Syndrome (MPS-III)
Morquio Syndrome (MPS-IV)

 

Maroteaux-Lamy Syndrome (MPS-VI)
Sly Syndrome (MPS-VII) (beta-glucuronidase deficiency)
Mucolipidosis II (I-cell Disease)
Leukodystrophy Disorders
Adrenoleukodystrophy (ALD)
Krabbe Disease (Globoid Cell Leukodystrophy)
Metachromatic Leukodystrophy
Pelizaeus-Merzbacher Disease
Lysosomal Storage Diseases Niemann-Pick Disease
Sandhoff Disease
Wolman Disease
Other Lesch-Nyhan Syndrome
Osteoporosis/Osteopetrosis

*Note: The Sources of disease information are under “ Literature & References”